Satellite imagery and AI are transforming water quality and pollution monitoring across Asia-Pacific. In the Philippines, where an estimated 540,000 tons of plastic leak into waterways each year, these technologies provide continuous, wide-area surveillance from Manila Bay to inland freshwater systems. By combining multi-sensor satellite data with predictive models, stakeholders can map plastic pollution hotspots, forecast harmful algal blooms (HABs), and assess ecosystem health in near real-time – revealing vital links between water quality and public health. This data-driven approach enables evidence-based policy and targeted interventions, while cross-sector partnerships translate insights into action – protecting communities, reducing pollution, and advancing sustainable development goals.