Irakli is a Mathematical Biologist. He obtained his MA and PhD degrees in mathematics at Arizona State University. He then worked as a postdoc at Princeton University, where in 2002 he postulated that rising atmospheric carbon dioxide levels (CO2) decrease the concentrations of minerals essential for human nutrition, including iron and zinc, in plants globally.
After years of compiling data, in 2014 he published a meta-analysis revealing a pervasive and systemic downshift in mineral levels in plants worldwide. His research came to influence US policy and was highlighted by New Scientist, Nature, Science, and in a two-times award winning article in Politico. This year, Loladze and collaborators showed that rising CO2 levels result in lower levels of plant carotenoids critical for human eye and brain health.